Lists
Lists
Sil dos Santos, Bruno and Hilton, Stephen T. (2021) 2 - Epi-3,6-dithio-2,5-diketopiperazines (ETPs): an overview of synthetic approaches to the ETP core. In: Progress in Heterocyclic Chemistry. Volume 32. Elsevier, pp. 27-105. ISBN 9780323898133
This chapter reports on the different types of both monomeric and dimeric epi-3,6-dithio-2,5-diketopiperazines (ETPs). The ETP core chemical scaffold has been reported in over 100 natural products and their diverse antiviral, antifungal, antibacterial, and anticancer activities have attracted the interest of many researchers. Herein, we describe different examples and synthetic approaches attempted to obtain the ETP core structure, characterised by a diketopiperazine ring bridged by two (or more) sulfur atoms at the three and six positions.
 |
View Item |