Acetic Acid Catalysed One-Pot Synthesis of Pyrrolo[1,2-a]quinox- aline Derivatives

Allan, Pia N. M., Ostrowska, Martyna I. and Patel, Bhaven (2019) Acetic Acid Catalysed One-Pot Synthesis of Pyrrolo[1,2-a]quinox- aline Derivatives. Synlett, 30. A-E. ISSN 0936-5214

Abstract

An efficient acetic acid catalysed reaction has been developed for the synthesis of 4-aryl substituted pyrrolo[1,2-a]quinoxalines from readily available starting materials. A range of structures have been synthesised in very good to excellent yields. The one-pot reaction proceeds through imine formation, cyclisation followed by air oxidation.

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