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Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A

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Damai, Margarita, Guzzardi, Norman, Lewis, Viliyana, Rao, Zenobia X., Sykes, Daniel and Patel, Bhaven (2023) Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A. RSC Advances, 13 (42). pp. 29561-29567. ISSN 2046-2069

Abstract

The synthesis of mono- and novel bis-methylated pyrrolo[1,2-a]quinoxalines through the addition of unstable methyl radicals to aryl isocyanides is described contingent upon the reaction conditions employed. The strategy has been effectively employed in the total synthesis of the natural product marinoquinoline A.

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Title:
Crafting mono- and novel bis-methylated pyrroloquinoxaline derivatives from a shared precursor and its application in the total synthesis of marinoquinoline A
Creators:
Damai, Margarita, Guzzardi, Norman, Lewis, Viliyana, Rao, Zenobia X., Sykes, Daniel and Patel, Bhaven
Identification Number:
https://doi.org/10.1039/D3RA05952A
Official URL:
https://pubs.rsc.org/en/content/articlelanding/202...
Date:
10 October 2023
Subjects:
500 Natural Sciences and Mathematics > 540 Chemistry & allied sciences
Department:
School of Human Sciences
Publisher:
Royal Society of Chemistry
Uncontrolled Keywords:
chemical compounds; synthesis; pyrroloquinoxaline; marinoquinoline A
Record
URI:
https://repository.londonmet.ac.uk/id/eprint/8814
Item Type:
Article
Depositing User:
Bhaven Patel
Date Deposited:
16 Oct 2023 08:37
Revision:
25
Last Modified:
30 Oct 2023 15:16
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