The application of prophylactic antibodies for rhinovirus infections

Privolizzi, Riccardo and Solari, Roberto and Johnston, Sebastian L. and McLean, Gary R. (2014) The application of prophylactic antibodies for rhinovirus infections. Antiviral chemistry & chemotherapy, 23 (5). pp. 173-7. ISSN 2040-2066

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Abstract

Rhinoviruses are extremely common pathogens of the upper respiratory tract with adults experiencing on average 2-5 infections per year and children up to 12 infections. Although infections are not life threatening, except in cases of chronic lung disease where rhinoviruses are the major precipitant of acute exacerbations of disease, there is a high associated economic cost resulting from lost productivity due to absence from work or school. Treatment of infections focuses on symptom relief with anti-pyretics/analgesics as there are no antiviral therapies available and vaccine strategies face difficulties because of the large number of viral serotypes. Here, we assess the potential for prophylactic antibody intervention for these ubiquitous human pathogens.

Item Type: Article
Uncontrolled Keywords: prophylactic antibodies, rhinovirus infections, rhinoviruses, pathogens
Subjects: 600 Technology > 610 Medicine & health
Department: School of Human Sciences
Depositing User: Gary Mclean
Date Deposited: 03 Aug 2015 08:44
Last Modified: 18 Aug 2015 10:25
URI: http://repository.londonmet.ac.uk/id/eprint/654

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