2 - Epi-3,6-dithio-2,5-diketopiperazines (ETPs): an overview of synthetic approaches to the ETP core

Sil dos Santos, Bruno and Hilton, Stephen T. (2021) 2 - Epi-3,6-dithio-2,5-diketopiperazines (ETPs): an overview of synthetic approaches to the ETP core. In: Progress in Heterocyclic Chemistry. Volume 32. Elsevier, pp. 27-105. ISBN 9780323898133

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Official URL: https://doi.org/10.1016/B978-0-323-89812-6.00002-X

Abstract / Description

This chapter reports on the different types of both monomeric and dimeric epi-3,6-dithio-2,5-diketopiperazines (ETPs). The ETP core chemical scaffold has been reported in over 100 natural products and their diverse antiviral, antifungal, antibacterial, and anticancer activities have attracted the interest of many researchers. Herein, we describe different examples and synthetic approaches attempted to obtain the ETP core structure, characterised by a diketopiperazine ring bridged by two (or more) sulfur atoms at the three and six positions.

Item Type: Book Section
Uncontrolled Keywords: epi-3,6-dithio-2,5-diketopiperazines; ETP; synthesis of natural products
Subjects: 500 Natural Sciences and Mathematics > 540 Chemistry & allied sciences
Department: School of Human Sciences
Depositing User: Bruno Da Silva sil dos santos
Date Deposited: 22 Apr 2021 10:12
Last Modified: 22 Apr 2021 10:13
URI: http://repository.londonmet.ac.uk/id/eprint/6527

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