COVID‐19 comorbidities, associated procoagulant extracellular vesicles and venous thromboembolisms: a possible link with ethnicity?

Inal, Jameel (2020) COVID‐19 comorbidities, associated procoagulant extracellular vesicles and venous thromboembolisms: a possible link with ethnicity? British Journal of Haematology, 190 (4). ISSN 1365-2141

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Official URL: https://doi.org/10.1111/bjh.17011

Abstract / Description

In view of numerous recent reports describing increased risks of thrombosis in coronavirus disease 2019 (COVID-19) amongst certain ethnicities in which co-morbidities are more prevalent, besides the identified risk factors, procoagulant plasma extracellular vesicles have not been considered. Several comorbidities predict mortality in patients with COVID19, some of which are more prevalent in Black, Asian and Minority Ethnic (BAME) groups. In a meta-analysis of seven studies (1,576 infected patients) the co-morbidities included hypertension (21.1%), diabetes (9.7%), cardiovascular disease (CVD), (8.4%) and respiratory system disease (1.5%). Of the critically ill COVID-19 patients with these co-morbidities and an associated hyperinflammatory state admitted to intensive care units (ICUs), up to 31% suffered thrombotic episodes (even with thromboprophylaxis), in particular, venous thromboembolisms (VTE), one of the important sequelae of COVID-19.

Item Type: Article
Additional Information: "This is the peer reviewed version of the following article: Inal, J. (2020) COVID‐19 comorbidities, associated procoagulant extracellular vesicles and venous thromboembolisms: a possible link with ethnicity? British Journal of Haematology (1365-2141), which has been published in final form at https://doi.org/10.1111/bjh.17011. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions." -- Wiley's Self-Archiving Policy
Uncontrolled Keywords: COVID-19, venous thrombosis, ethnicity, extracellular vesicles
Subjects: 600 Technology > 610 Medicine & health
Department: School of Human Sciences
SWORD Depositor: Pub Router
Depositing User: Pub Router
Date Deposited: 14 Aug 2020 12:46
Last Modified: 11 Sep 2020 14:49
URI: http://repository.londonmet.ac.uk/id/eprint/5959

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