Acetic Acid Catalysed One-Pot Synthesis of Pyrrolo[1,2-a]quinox- aline Derivatives

Allan, Pia N. M., Ostrowska, Martyna I. and Patel, Bhaven (2019) Acetic Acid Catalysed One-Pot Synthesis of Pyrrolo[1,2-a]quinox- aline Derivatives. Synlett, 30. A-E. ISSN 0936-5214

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Abstract / Description

An efficient acetic acid catalysed reaction has been developed for the synthesis of 4-aryl substituted pyrrolo[1,2-a]quinoxalines from readily available starting materials. A range of structures have been synthesised in very good to excellent yields. The one-pot reaction proceeds through imine formation, cyclisation followed by air oxidation.

Item Type: Article
Uncontrolled Keywords: pyrrolo[1,2-a]quinoxaline, catalysis, Pictet–Spengler reac-tion, 1-(2-aminophenyl)pyrroles, biological heterocycles
Subjects: 500 Natural Sciences and Mathematics > 540 Chemistry & allied sciences
Department: School of Human Sciences
Depositing User: Bhaven Patel
Date Deposited: 28 Oct 2019 10:39
Last Modified: 28 Oct 2019 10:39
URI: http://repository.londonmet.ac.uk/id/eprint/5235

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