St Claire Green, Donovan (1991) The synthesis of aminophosphonic acid derivatives & related compounds. Doctoral thesis, Polytechnic of North London.
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Abstract / Description
1-Aminoalkanephosphonic acids and their derivatives, have long been claimed to be compounds with a wide variety of application. Numerous examples exist where they have been described as: complex-forming agents with sequestrating properties, extractants, wetting agents, pharmaceutical preparations, ion exchangers, herbicides, compounds with plant growth regulatory activity; inhibitors of aminopeptidases; as structural units in peptide analogues, functioning as antibacterial agents, which inhibit bacterial cell wall biosynthesis; as structural units in peptidic phosphonylating agents that irreversibly inhibit a wide variety of serine proteases; as structural units in butyloxycarbonyl protected phosphonate esters that complex with alpha-lytic proteases; and as structural units in peptidyl phosphonate diphenyl 9 10 esters which powerfully inhibit the enzyme thrombin. …
Item Type: | Thesis (Doctoral) |
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Additional Information: | uk.bl.ethos.295019 |
Subjects: | 500 Natural Sciences and Mathematics > 540 Chemistry & allied sciences |
Department: | School of Human Sciences |
Depositing User: | Maria White |
Date Deposited: | 20 Sep 2018 13:06 |
Last Modified: | 20 Sep 2018 13:06 |
URI: | https://repository.londonmet.ac.uk/id/eprint/3256 |
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