Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies

Da Silva Sil Dos Santos, Bruno and Moore, David J. (2018) Use of LC-MS analysis to elucidate by-products of niacinamide transformation following in vitro skin permeation studies. International journal of cosmetic science. ISSN 1468-2494

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Abstract / Description

Pyridine-3-carboxamide, also known as niacinamide (NIA), is used in many pharmaceutical and personal care formulations for the improvement of skin barrier function, management of acne and amelioration of the symptoms of atopic dermatitis [1-3]. The widespread use of NIA (Table I) in skin care highlights the importance of understanding the percutaneous penetration and skin distribution of this molecule [4]. Previously, we have conducted several studies that have evaluated a wide variety of NIA formulations [4, 5].

Item Type: Article
Additional Information: ** From PubMed via Jisc Publications Router. [Abstract copyright: This article is protected by copyright. All rights reserved.]
Subjects: 600 Technology > 610 Medicine & health
Department: School of Human Sciences
SWORD Depositor: Pub Router
Depositing User: Pub Router
Date Deposited: 14 Sep 2018 12:00
Last Modified: 14 Sep 2018 12:00
URI: http://repository.londonmet.ac.uk/id/eprint/2869

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