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Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites

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Yu, Deng-Guang, White, Kenneth, Chatterton, Nicholas, Li, Ying, Li, Lingling and Wang, Xia (2015) Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites. RSC Advances, 5. pp. 9462-9466. ISSN 2046-2069

Abstract

Electrospun polymeric core–shell nanocomposites are exploited as templates to manipulate molecular self-assembly for preparing structural lipid nanoparticles, during which the confinement effect of fibers together with their core–shell structure, the aqueous environment and the secondary interactions, all contributed synergistically to facilitate molecular self-aggregation to produce lipid nanoparticles with a drug entrapment efficiency of 95.9% with a sustained drug release profile.

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Title:
Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites
Creators:
Yu, Deng-Guang, White, Kenneth, Chatterton, Nicholas, Li, Ying, Li, Lingling and Wang, Xia
Identification Number:
https://doi.org/10.1039/c4ra14001j
Official URL:
http://www.rsc.org/advances
Date:
2015
Subjects:
500 Natural Sciences and Mathematics > 540 Chemistry & allied sciences
Department:
School of Human Sciences
Publisher:
Royal Society of Chemistry
Uncontrolled Keywords:
electrospinning, self-assembly, nanoparticles
Record
URI:
https://repository.londonmet.ac.uk/id/eprint/1034
Item Type:
Article
Depositing User:
Kenneth White
Date Deposited:
28 Jun 2016 09:14
Revision:
13
Last Modified:
04 Jun 2020 11:56
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