Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites

Yu, Deng-Guang and White, Kenneth and Chatterton, Nicholas and Li, Ying and Li, Lingling and Wang, Xia (2015) Structural lipid nanoparticles self-assembled from electrospun core-shell polymeric nanocomposites. RSC Advances, 5. pp. 9462-9466. ISSN 2046-2069

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Abstract

Electrospun polymeric core–shell nanocomposites are exploited as templates to manipulate molecular self-assembly for preparing structural lipid nanoparticles, during which the confinement effect of fibers together with their core–shell structure, the aqueous environment and the secondary interactions, all contributed synergistically to facilitate molecular self-aggregation to produce lipid nanoparticles with a drug entrapment efficiency of 95.9% with a sustained drug release profile.

Item Type: Article
Uncontrolled Keywords: electrospinning, self-assembly, nanoparticles
Subjects: 500 Natural Sciences and Mathemetics > 540 Chemistry & allied sciences
Department: School of Human Sciences
Depositing User: Kenneth White
Date Deposited: 28 Jun 2016 09:14
Last Modified: 28 Jun 2016 09:14
URI: http://repository.londonmet.ac.uk/id/eprint/1034

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